Lexeo Therapeutics is a leading biotechnology company specializing in the development of novel gene therapies for rare genetic diseases. Leveraging cutting-edge research and innovative technologies, Lexeo is dedicated to transforming the treatment landscape for patients with unmet medical needs.

lexeo_therapeutics

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<p><span data-contrast="auto">Role Summary</span><span data-ccp-props="{}">&nbsp;</span></p>
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<p><span data-contrast="none">The&nbsp;Research Associate I/II will support Lexeo’s human induced pluripotent stem cell–derived cardiomyocyte (iPSC-CM) platform, a core in vitro system used to evaluate target engagement, mechanism of action, and potency across discovery and preclinical programs. This hands-on laboratory role will execute established cellular and molecular assays, contribute to assay development, and generate high-quality data. The position reports to the Head of Cardiac Research and receives day-to-day scientific direction from the Preclinical Scientist leading the platform. This is an exciting opportunity to join a cutting-edge drug discovery team advancing new therapies for patients with genetic heart disease while gaining valuable experiences for a future career in biotech and medicine</span><span data-ccp-props="{}">&nbsp;</span></p>
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Research Associate I/II, Preclinical Research (Contract)

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<p><span data-contrast="auto">Role Summary</span><span data-ccp-props="{}">&nbsp;</span></p>
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<p><span data-contrast="none">The Manager/Senior Manager, CMC Quality Control (QC) is responsible for providing strategic and operational oversight of QC activities supporting Lexeo's gene therapy programs. This role serves as a QC lead for external contract testing laboratories (CTLs), analytical lifecycle management (i.e., late-phase method validation), stability programs, release testing support, and analytical investigation activities.</span><span data-ccp-props="{}">&nbsp;</span></p>
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<p><span data-contrast="none">The individual will work closely with Analytical Development, Technical Operations, Regulatory Affairs, Quality Assurance, and external partners to ensure analytical methods, specifications, and testing programs support clinical development, process validation readiness, and future commercial requirements.</span><span data-ccp-props="{}">&nbsp;</span></p>
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<p><span data-contrast="none">This position requires technical expertise in analytical testing, preferably of AAV-based products, as well as demonstrated experience overseeing external laboratories and driving cross-functional CMC initiatives.</span><span data-ccp-props="{}">&nbsp;</span></p>
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Manager/Senior Manager, CMC Quality Control

<div> <div> <p><span data-contrast="auto">Role Summary</span><span data-ccp-props="{}">&nbsp;</span></p> </div> <div> <p><span data-contrast="auto">Lexeo is seeking an experienced and motivated </span><span data-contrast="auto">clinical development&nbsp;leader to advance late-stage development programs&nbsp;as a key member of our development team. This individual will report to the&nbsp;Vice President, Clinical Development&nbsp;and will provide strategic and hands-on leadership across clinical strategy, study execution, and cross-functional integration to deliver high-quality evidence to support regulatory interactions and submissions (e.g., BLA). This role requires strong scientific and operational judgment and the ability to build effective partnerships with internal stakeholders and external collaborators.</span><span data-ccp-props="{}">&nbsp;</span></p> </div> </div>

Senior Director, Clinical Development

<div> <div> <p>Role Summary</p> </div> <div> <p><span data-contrast="auto">We are looking for a talented and highly motivated contract Lab Operations Associate Scientist/Scientist I to join the Lexeo Team in NYC to support the operations within our gene therapy laboratory.</span><span data-ccp-props="{}">&nbsp;</span></p> </div> <div> <p><span data-contrast="auto">You will be expected to support the daily operations of the laboratory, ensuring that workflows run smoothly, safely, and efficiently. This role reports to the Lab Manager to oversee equipment, procure supplies, manage shipments, and ensure compliance with safety standards. The ideal candidate is organized, detail-</span><span data-contrast="auto">oriented, and comfortable balancing administrative responsibilities with hands</span>‑<span data-contrast="auto">on lab support.&nbsp;&nbsp;The nature of the role will require in-person work.</span><span data-ccp-props="{}">&nbsp;</span></p> </div> </div>

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