Rapport Therapeutics is a biotechnology company focused on developing innovative therapies for a wide range of diseases. With a commitment to advancing healthcare through cutting-edge research and development, Rapport Therapeutics aims to revolutionize the treatment landscape and improve patient outcomes.

rapport-therapeutics

<div class="content-intro">When our people share why they joined Rapport and love it here, it comes down to three things: the science, the mission, and the team. At Rapport, we’re driven by a passion for developing precision neuromedicines with the potential for fewer side effects, enabling patients and their families to enjoy healthier, more fulfilling lives. And we’re doing this with extraordinary science and awesome people (affectionately called Rapptors).&nbsp;
Our innovative scientific platform is centered on Receptor Associate Proteins (RAPs). RAPs are a component of neuronal receptor complexes, which play a crucial role in regulating receptor assembly and function. This precision approach has the potential to revolutionize the development of small molecule therapies. We are excited about the potential of our lead program, RAP-219. Our first indication targets focal epilepsy with additional clinical trials in primary generalized tonic-clonic seizures (PGTCS) and bipolar disorder.
The strength of Rapport comes from our Rapptors – who are united by our mission to improve patients lives. We bring the heart and hustle to advance our science forward, always staying true to our core values. We hope you’re as excited about this opportunity as we are!</div>This role is based in Boston, MA with onsite presence required Monday-Wednesday
Your impact:
As our Director of Clinical Contracts, you’ll help turn clinical plans into action. You’ll own clinical trial agreements, site budgets, and vendor contracts while partnering with Clinical Ops, Legal, Finance, and our CROs to keep studies moving. You’ll help build a contracting process that keeps pace with our growing global portfolio.
Your day-to-day:&nbsp;&nbsp;
<ul>
<li>Develop, own, and maintain clinical contract lifecycle strategy (templates, fallback language, and negotiation playbooks) to standardize contracting process as the portfolio scales globally.</li>
<li>Review and negotiate site Clinical Trial Agreements (CTAs) and CDAs</li>
<li>Develop and align contracting strategy with clinical development plan, shaping negotiation strategy and risk tolerances in line with the pipeline stage (e.g., trial scale-up, new geographies).</li>
<li>Lead end-to-end drafting, review, and negotiation of Confidentiality Disclosure Agreements (CDAs), Master Service Agreements (MSAs), Material Transfer Agreements (MTAs), Statements of Work (SOWs), License Agreements, Subscription Agreements</li>
<li>Partner closely with Clinical Operations, outside counsel, Finance, and CRO/vendor teams to design a preferred vendor program and align contract terms with study timelines and budget parameters.</li>
<li>Serve as strategic advisor to Clinical Operations surfacing contract risk, budget exposure, and portfolio-level trade-offs to inform program decisions.</li>
<li>Track contract status, cycle times, and site activation timelines; proactively identify and resolve bottlenecks.</li>
<li>Ensure all agreements comply with applicable regulations (FDA, ICH-GCP, GDPR and other privacy regulations), Fair Market Value (FMV) standards, and company policies.</li>
<li>Maintain accurate, audit-ready contract files and documentation in support of inspection readiness.</li>
<li>Lead technology and process strategy for the Contracts function, including selection, rollout, integration, use of AI and governance of systems and tools, including buy vs. build decisions.</li>
<li>Develop and implement AI strategy and roadmap for the contracts function</li>
<li>Support department headcount plan and structure; hire, mentor and develop a growing team of contract professionals.</li>
</ul>
Must-Haves:
<ul>
<li>Bachelor's degree required</li>
<li>10+ years of experience reviewing and negotiating clinical trial agreements, and/or related vendor contracts within a biotech, pharmaceutical, or clinical CRO environment.</li>
<li>Experience with strategic level decision making for the Contracts function.</li>
<li>Demonstrated executive presence, with experience advising senior leadership on contracting risk and strategy</li>
<li>Experience building, leading, and developing a contracts team.</li>
<li>Global contract experience, including familiarity with international site contracting and cross-border legal/privacy considerations.</li>
<li>Deep familiarity with clinical trial agreement structures, and FMV principles.</li>
<li>Working knowledge of FDA regulations and ICH-GCP guidelines as they pertain to clinical contracting.</li>
<li>Strong negotiation skills with a track record of driving agreements to execution efficiently.</li>
<li>Excellent cross-functional collaboration skills, with experience partnering across Legal, Finance, Development, CMC, Quality, Biometrics, Bioanalytics, Regulatory, and Clinical Operations.</li>
<li>Highly organized, with strong attention to detail and the ability to manage a high volume of contracts simultaneously.</li>
</ul>
What makes Rapport special:
<ul>
<li>Every role has meaning. We’re determined to discover a better way for patients, and you’ll feel the passion from the start.</li>
<li>We are driven to innovate. Exciting science that pushes boundaries and opens new possibilities.</li>
<li>Your perspective matters. Stick your neck out, share your ideas – we work as a team.</li>
<li>We have FUN. We hire smart, dedicated, down-to-earth people that you’ll enjoy spending time with.</li>
<li>Leadership that CARES – about you, your growth + development.</li>
<li>We're bicoastal. Whether you're in the lab full-time in San Diego or taking advantage of a more hybrid work schedule in Boston – we make the most of our time together.</li>
<li>Competitive benefits. Including unlimited PTO, a lifestyle spending account, commuting reimbursement, and much more!</li>
<li>You get to be YOU! Show up as you are and make every day count.</li>
</ul>
Your Compensation:
We get it. Compensation is an important part of your offer. You shouldn’t be surprised at the end of the recruiting process, and you should know that your offer is fair and equitable. How do we do this?&nbsp; We tell you about our hiring range now - we expect the hiring range for the role to be $195,000 to $215,000 for the Director level. Our actual offer will reflect a lot of factors including your relevant skills, experience, location, salary market data, and internal equity. In addition to a competitive salary, we also offer a pretty great benefits package. We don’t stop here - if you join Rapport, we go to the next level. We share our full salary ranges for every level across our company.&nbsp;
Hybrid Work Environment:
We prioritize in person connection with our fellow Rapptors! Our team members come together onsite at our Boston office Monday-Wednesday to create more opportunities for innovation, collaboration, and connection.
&nbsp;<div class="content-conclusion">Rapport Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.
Note to Employment Agencies: Please do not forward any agency resumes. The company will not be responsible for any fees related to resumes that are unsolicited.
CCPA disclosure notice can be found <a href="https://www.rapportrx.com/privacy-policy/" target="_blank">here</a>.&nbsp;</div>

Director, Clinical Contracts

<div class="content-intro">When our people share why they joined Rapport and love it here, it comes down to three things: the science, the mission, and the team. At Rapport, we’re driven by a passion for developing precision neuromedicines with the potential for fewer side effects, enabling patients and their families to enjoy healthier, more fulfilling lives. And we’re doing this with extraordinary science and awesome people (affectionately called Rapptors).&nbsp;
Our innovative scientific platform is centered on Receptor Associate Proteins (RAPs). RAPs are a component of neuronal receptor complexes, which play a crucial role in regulating receptor assembly and function. This precision approach has the potential to revolutionize the development of small molecule therapies. We are excited about the potential of our lead program, RAP-219. Our first indication targets focal epilepsy with additional clinical trials in primary generalized tonic-clonic seizures (PGTCS) and bipolar disorder.
The strength of Rapport comes from our Rapptors – who are united by our mission to improve patients lives. We bring the heart and hustle to advance our science forward, always staying true to our core values. We hope you’re as excited about this opportunity as we are!</div>We anticipate hiring for this role in mid-Q4.&nbsp;This role is located in Boston, MA with an onsite requirement of Monday-Wednesday every week.
Your impact:
Translate&nbsp;compelling&nbsp;science&nbsp;into&nbsp;a clinic-ready programs&nbsp;with the speed and rigor&nbsp;a maturing&nbsp;biotech demands.&nbsp;
Your day-to-day:
<ul>
<li>Serve as the single accountable leader for two assigned programs (RAP-641 and one other) from late discovery and IND-filing and through Phase 1 and Phase 2 clinical trials.&nbsp;</li>
<li data-leveltext="" data-font="Symbol" data-listid="4" data-list-defn-props="{&quot;335552541&quot;:1,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;&quot;,&quot;469777815&quot;:&quot;hybridMultilevel&quot;}" data-aria-posinset="2" data-aria-level="1">Build and lead cross-functional program teams (Discovery, Toxicology, CMC, Regulatory, Clinical, Biostatistics,&nbsp;New Product Planning) to align on target product profile,&nbsp;integrated&nbsp;development&nbsp;strategy, and&nbsp;key study designs&nbsp;that&nbsp;align with corporate goals and regulatory expectations.&nbsp;</li>
<li data-leveltext="" data-font="Symbol" data-listid="4" data-list-defn-props="{&quot;335552541&quot;:1,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;&quot;,&quot;469777815&quot;:&quot;hybridMultilevel&quot;}" data-aria-posinset="2" data-aria-level="1">Partner with Regulatory Affairs to shape IND-enabling package strategy and pre-IND/IND interactions with health authorities&nbsp;</li>
<li data-leveltext="" data-font="Symbol" data-listid="4" data-list-defn-props="{&quot;335552541&quot;:1,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;&quot;,&quot;469777815&quot;:&quot;hybridMultilevel&quot;}" data-aria-posinset="2" data-aria-level="1">Translate preclinical and translational data into clear go/no-go criteria and decision frameworks for governance bodies and the executive team&nbsp;</li>
<li data-leveltext="" data-font="Symbol" data-listid="4" data-list-defn-props="{&quot;335552541&quot;:1,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;&quot;,&quot;469777815&quot;:&quot;hybridMultilevel&quot;}" data-aria-posinset="2" data-aria-level="1">Partner with Program Managers&nbsp;to develop and manage integrated program timelines, budgets, and risk registers; proactively&nbsp;identify and mitigate technical, regulatory, and operational risks</li>
<li data-leveltext="" data-font="Symbol" data-listid="4" data-list-defn-props="{&quot;335552541&quot;:1,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;&quot;,&quot;469777815&quot;:&quot;hybridMultilevel&quot;}" data-aria-posinset="2" data-aria-level="1">Serve as the primary internal voice of the program in portfolio reviews, board updates, and investor-facing materials, in partnership with Commercial and IR&nbsp;</li>
<li data-leveltext="" data-font="Symbol" data-listid="4" data-list-defn-props="{&quot;335552541&quot;:1,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;&quot;,&quot;469777815&quot;:&quot;hybridMultilevel&quot;}" data-aria-posinset="2" data-aria-level="1">Build strong relationships with key internal stakeholders and external partners (CROs, CDMOs, consultants, etc.)</li>
<li data-leveltext="" data-font="Symbol" data-listid="4" data-list-defn-props="{&quot;335552541&quot;:1,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;&quot;,&quot;469777815&quot;:&quot;hybridMultilevel&quot;}" data-aria-posinset="2" data-aria-level="1">Mentor junior program management staff and help build program management capability as the organization scales&nbsp;</li>
</ul>
Must-Haves:
<ul>
<li>PhD, PharmD, MD, or equivalent advanced degree in a relevant scientific or clinical field.</li>
<li>15+ years of biotech/pharmaceutical industry experience, with proven leadership in small molecule drug development.</li>
<li>Significant experience&nbsp;leading cross-functional programs&nbsp;from&nbsp;discovery&nbsp;through&nbsp;IND submission and&nbsp;early&nbsp;stages&nbsp;of development&nbsp;&nbsp;</li>
<li>Strong understanding of regulatory pathways and expectations for small molecule therapeutics.</li>
<li>Exceptional interpersonal, communication, and influencing skills.</li>
<li>Strong scientific fluency across pharmacology, toxicology, and clinical development, with the judgment to synthesize input from technical experts into clear strategic recommendations&nbsp;</li>
<li data-leveltext="" data-font="Symbol" data-listid="4" data-list-defn-props="{&quot;335552541&quot;:1,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;&quot;,&quot;469777815&quot;:&quot;hybridMultilevel&quot;}" data-aria-posinset="14" data-aria-level="1">Track record&nbsp;operating effectively in small, resource-constrained organizations — comfortable with ambiguity and direct execution, not just oversight&nbsp;</li>
<li data-leveltext="" data-font="Symbol" data-listid="4" data-list-defn-props="{&quot;335552541&quot;:1,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;&quot;,&quot;469777815&quot;:&quot;hybridMultilevel&quot;}" data-aria-posinset="14" data-aria-level="1">Excellent executive communication skills; experience presenting to senior leadership and boards&nbsp;</li>
</ul>
&nbsp;
What makes Rapport special:
<ul>
<li>Every role has meaning. We’re determined to discover a better way for patients, and you’ll feel the passion from the start.</li>
<li>We are driven to innovate. Exciting science that pushes boundaries and opens new possibilities.</li>
<li>Your perspective matters. Stick your neck out, share your ideas – we work as a team.</li>
<li>We have FUN. We hire smart, dedicated, down-to-earth people that you’ll enjoy spending time with.</li>
<li>Leadership that CARES – about you, your growth + development.</li>
<li>We're bicoastal. Whether you're in the lab full-time in San Diego or taking advantage of a more hybrid work schedule in Boston – we make the most of our time together.</li>
<li>Competitive benefits. Including unlimited PTO, a lifestyle spending account, commuting reimbursement, and much more!</li>
<li>You get to be YOU! Show up as you are and make every day count.</li>
</ul>
&nbsp;
We get it. Compensation is an important part of your offer. You shouldn’t be surprised at the end of the recruiting process, and you should know that your offer is fair and equitable. How do we do this?&nbsp; We tell you about our hiring range now - we expect the hiring range for this role to be $310,000 to $340,000. Our actual offer will reflect a lot of factors including your relevant skills, experience, location, salary market data, and internal equity. In addition to a competitive salary, we also offer a pretty great benefits package. We don’t stop here - if you join Rapport, we go to the next level. We share our full salary ranges for every level across our company.
&nbsp;
&nbsp;
Hybrid Work Environment:
We prioritize in person connection with our fellow Rapptors! Our team members come together onsite at our Boston office Monday-Wednesday to create more opportunities for innovation, collaboration, and connection.
&nbsp;
&nbsp;
&nbsp;<div class="content-conclusion">Rapport Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.
Note to Employment Agencies: Please do not forward any agency resumes. The company will not be responsible for any fees related to resumes that are unsolicited.
CCPA disclosure notice can be found <a href="https://www.rapportrx.com/privacy-policy/" target="_blank">here</a>.&nbsp;</div>

VP, Program Leader

<div class="content-intro">When our people share why they joined Rapport and love it here, it comes down to three things: the science, the mission, and the team. At Rapport, we’re driven by a passion for developing precision neuromedicines with the potential for fewer side effects, enabling patients and their families to enjoy healthier, more fulfilling lives. And we’re doing this with extraordinary science and awesome people (affectionately called Rapptors).&nbsp;
Our innovative scientific platform is centered on Receptor Associate Proteins (RAPs). RAPs are a component of neuronal receptor complexes, which play a crucial role in regulating receptor assembly and function. This precision approach has the potential to revolutionize the development of small molecule therapies. We are excited about the potential of our lead program, RAP-219. Our first indication targets focal epilepsy with additional clinical trials in primary generalized tonic-clonic seizures (PGTCS) and bipolar disorder.
The strength of Rapport comes from our Rapptors – who are united by our mission to improve patients lives. We bring the heart and hustle to advance our science forward, always staying true to our core values. We hope you’re as excited about this opportunity as we are!</div>&nbsp;
We anticipate hiring for this role in mid-Q4.&nbsp;This role is located in Boston, MA with an onsite requirement of Monday-Wednesday every week.
&nbsp;
Your impact:
As a Senior Clinical Trial Associate, you’ll be a key player in keeping our Bipolar Mania studies on track—managing the details, supporting the team, and helping bring innovative treatments to patients
Your day-to-day:&nbsp;&nbsp;
<ul>
<li>Coordinates and tracks the distribution and subsequent retrieval of clinical documents, including but not limited to protocols, protocol amendments, IBs, ICF's, monitoring visit reports, etc.</li>
<li>Supports maintenance of inspection-ready Trial Master File (TMF) according to ICH-GCP and company SOPs</li>
<li>Perform quality checks on the study TMF with oversight of study COL</li>
<li>Assists in the preparation of study related documents, i.e., ICF, clinical trial tools and templates, etc. May coordinate and track clinical trial equipment and supplies</li>
<li>Review and track vendor invoices against contracts with oversight of study COL</li>
<li>Coordinates and tracks administrative aspects of contract execution and PO generation</li>
<li>Supports the trial team to produce and distribute study newsletters</li>
<li>Supports collection and updating of clinical trial insurance</li>
<li>Supports posting of all agreed clinical trials to publicly available websites</li>
<li>Assists with various supportive trial activities, i.e., meeting management including agenda distribution and minute taking, internal database maintenance, study team contact list, etc.</li>
<li>May support additional ad-hoc activities as agreed with the study COL</li>
</ul>
Must-Haves:
<ul>
<li>Bachelor's degree in life sciences or healthcare related field</li>
<li>3+ years' experience in a clinical trial support position, experience in Biotech or Pharma strongly preferred</li>
<li>Strong computer skills including knowledge of Excel, Word, PowerPoint and Outlook</li>
<li>Solid understanding of the responsibilities and needs of other functions in a clinical trial</li>
<li>Proven ability to work independently and effectively handle multiple priorities in a fast-paced environment</li>
<li>Ability to multitask and flex across projects as priorities and deadlines shift</li>
<li>Ability to maintain confidentiality of proprietary information</li>
<li>A team player that takes initiative and is proactive&nbsp;</li>
</ul>
What makes Rapport special:
<ul>
<li>Every role has meaning. We’re determined to discover a better way for patients, and you’ll feel the passion from the start.</li>
<li>We are driven to innovate. Exciting science that pushes boundaries and opens new possibilities.</li>
<li>Your perspective matters. Stick your neck out, share your ideas – we work as a team.</li>
<li>We have FUN. We hire smart, dedicated, down-to-earth people that you’ll enjoy spending time with.</li>
<li>Leadership that CARES – about you, your growth + development.</li>
<li>We're bicoastal. Whether you're in the lab full-time in San Diego or taking advantage of a more hybrid work schedule in Boston – we make the most of our time together.</li>
<li>Competitive benefits. Including unlimited PTO, a lifestyle spending account, commuting reimbursement, and much more!</li>
<li>You get to be YOU! Show up as you are and make every day count.</li>
</ul>
Your Compensation:
We get it. Compensation is an important part of your offer. You shouldn’t be surprised at the end of the recruiting process, and you should know that your offer is fair and equitable. How do we do this?&nbsp; We tell you about our hiring range now - we expect the hiring range for the role to be $90,000 to $110,000. Our actual offer will reflect a lot of factors including your relevant skills, experience, location, salary market data, and internal equity. In addition to a competitive salary, we also offer a pretty great benefits package. We don’t stop here - if you join Rapport, we go to the next level. We share our full salary ranges for every level across our company.&nbsp;
Hybrid Work Environment:
We prioritize in person connection with our fellow Rapptors! Our team members come together onsite at our Boston office Monday-Wednesday to create more opportunities for innovation, collaboration, and connection.
&nbsp;<div class="content-conclusion">Rapport Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.
Note to Employment Agencies: Please do not forward any agency resumes. The company will not be responsible for any fees related to resumes that are unsolicited.
CCPA disclosure notice can be found <a href="https://www.rapportrx.com/privacy-policy/" target="_blank">here</a>.&nbsp;</div>

Sr. Clinical Trial Associate

<div class="content-intro">When our people share why they joined Rapport and love it here, it comes down to three things: the science, the mission, and the team. At Rapport, we’re driven by a passion for developing precision neuromedicines with the potential for fewer side effects, enabling patients and their families to enjoy healthier, more fulfilling lives. And we’re doing this with extraordinary science and awesome people (affectionately called Rapptors).&nbsp;
Our innovative scientific platform is centered on Receptor Associate Proteins (RAPs). RAPs are a component of neuronal receptor complexes, which play a crucial role in regulating receptor assembly and function. This precision approach has the potential to revolutionize the development of small molecule therapies. We are excited about the potential of our lead program, RAP-219. Our first indication targets focal epilepsy with additional clinical trials in primary generalized tonic-clonic seizures (PGTCS) and bipolar disorder.
The strength of Rapport comes from our Rapptors – who are united by our mission to improve patients lives. We bring the heart and hustle to advance our science forward, always staying true to our core values. We hope you’re as excited about this opportunity as we are!</div>We anticipate hiring for this role in mid-Q4.&nbsp;
Your impact:
This Medical Director role offers the opportunity to partner closely with cross-functional leaders to support both clinical development and strategic initiatives in support of the RAP-219 Bipolar Mania program. The position provides broad exposure to multiple programs, with the chance to work hands-on in the details while growing within a fast-paced, innovative organization.
Your day-to-day:&nbsp; 
<ul>
<li>Provision of medical input for all clinical deliverables in Rapport’s lead program, RAP-219, related to Bipolar Mania</li>
<li>Driving execution of the assigned clinical program and/or clinical trial in partnership with clinical operations</li>
<li>Contributing to the development of regulatory documents in support of regulatory submissions, including the clinical sections of INDs and CTAs, safety reports, responses to regulatory authorities and Ethics Committees/IRBs, and other documents as appropriate</li>
<li>Ensuring that scientific rigor and innovation is at the forefront our Rapport’s clinical development strategy and implementation</li>
<li>Managing engagements with external organizations, key opinion leaders, and advisors</li>
<li>Supporting medical input into clinical development strategy and protocol reviews</li>
<li>Working closely with functional partners (Clinical Operations, Data Management, Biostatistics, Regulatory, Medical Affairs) to ensure an integrated and strategic approach to flawless execution and systematic oversight of study protocols</li>
<li>Establishing strong collaborations with study investigators and outside medical experts and representing Rapport during investigator meetings and advisory boards</li>
<li>Serving as the medical monitor for assigned studies including design, execution, cleaning, and interpretation of study data</li>
</ul>
Must-Haves:
<ul>
<li>MD or equivalent medical degree is required</li>
<li>Minimum of 2 years’ experience working in the biotech/pharmaceutical industry in clinical research or drug development</li>
<li>Strongly preferred advanced knowledge and clinical training and/or drug development experience in Psychiatry</li>
<li>Proven clinical development strategist with hands-on experience of designing, implementing, and conducting clinical trials in neurology, Phase 2a – Phase 3</li>
<li>Working knowledge of psychiatry indications is required, with proven ability to interpret, discuss and present efficacy and safety data relating to clinical trial(s) and proven ability to understand and interpret basic and clinical scientific research reports</li>
<li>Demonstrated ability to assimilate clinical data, perform thorough analysis and review, make crisp assessments, and communicate effectively both verbally and in writing</li>
<li>Demonstrated ability to establish effective scientific partnerships with key stakeholders</li>
<li>Working knowledge of GCP, clinical trial design, statistics, and regulatory and clinical development processes</li>
<li>Experience authoring regulatory documents, specifically exposure to the IND/NDA/BLA approval process</li>
<li>Ability to communicate and work both independently and collaboratively with colleagues across disciplines</li>
<li>Excellent oral presentation skills</li>
<li>Ability to think critically with demonstrable troubleshooting and problem-solving skills</li>
<li>Comfortable in a fast-paced small startup environment with minimal direction and able to adjust workload based upon changing priorities</li>
<li>Demonstrated ability to work effectively either independently or collaboratively in a cross-functional team environment, as well as with external colleagues.</li>
<li>Strong organizational, project management and leadership skills</li>
<li>Experience working cross-functionally, including consulting with key business stakeholders with an ability to influence for greater outcomes</li>
<li>Attention to detail and the ability to work individually, within a multi-disciplinary team, as well as with external partners and vendors</li>
<li>Possesses strong written and verbal communication skills</li>
</ul>
What makes Rapport special:
<ul>
<li>Every role has meaning. We’re determined to discover a better way for patients, and you’ll feel the passion from the start.</li>
<li>We are driven to innovate. Exciting science that pushes boundaries and opens new possibilities.</li>
<li>Your perspective matters. Stick your neck out, share your ideas – we work as a team.</li>
<li>We have FUN. We hire smart, dedicated, down-to-earth people that you’ll enjoy spending time with.</li>
<li>Leadership that CARES – about you, your growth + development.</li>
<li>We're bicoastal. Whether you're in the lab full-time in San Diego or taking advantage of a more hybrid work schedule in Boston – we make the most of our time together.</li>
<li>Competitive benefits. Including unlimited PTO, a lifestyle spending account, commuting reimbursement, and much more!</li>
<li>You get to be YOU! Show up as you are and make every day count.</li>
</ul>
Your Compensation:
We get it. Compensation is an important part of your offer. You shouldn’t be surprised at the end of the recruiting process, and you should know that your offer is fair and equitable. How do we do this?&nbsp; We tell you about our hiring range now - we expect the hiring range for the role to be $285,000 to $350,000. Our actual offer will reflect a lot of factors including your relevant skills, experience, location, salary market data, and internal equity. In addition to a competitive salary, we also offer a pretty great benefits package. We don’t stop here - if you join Rapport, we go to the next level. We share our full salary ranges for every level across our company.&nbsp;
Hybrid Work Environment:
We prioritize in person connection with our fellow Rapptors! Our team members come together onsite at our Boston office Monday-Wednesday to create more opportunities for innovation, collaboration, and connection.
&nbsp;<div class="content-conclusion">Rapport Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.
Note to Employment Agencies: Please do not forward any agency resumes. The company will not be responsible for any fees related to resumes that are unsolicited.
CCPA disclosure notice can be found <a href="https://www.rapportrx.com/privacy-policy/" target="_blank">here</a>.&nbsp;</div>

(Senior) Medical Director, Psychiatry

<div class="content-intro">When our people share why they joined Rapport and love it here, it comes down to three things: the science, the mission, and the team. At Rapport, we’re driven by a passion for developing precision neuromedicines with the potential for fewer side effects, enabling patients and their families to enjoy healthier, more fulfilling lives. And we’re doing this with extraordinary science and awesome people (affectionately called Rapptors).&nbsp;
Our innovative scientific platform is centered on Receptor Associate Proteins (RAPs). RAPs are a component of neuronal receptor complexes, which play a crucial role in regulating receptor assembly and function. This precision approach has the potential to revolutionize the development of small molecule therapies. We are excited about the potential of our lead program, RAP-219. Our first indication targets focal epilepsy with additional clinical trials in primary generalized tonic-clonic seizures (PGTCS) and bipolar disorder.
The strength of Rapport comes from our Rapptors – who are united by our mission to improve patients lives. We bring the heart and hustle to advance our science forward, always staying true to our core values. We hope you’re as excited about this opportunity as we are!</div>We anticipate hiring for this role in mid-Q4.&nbsp;The preferred location for this role is in Boston, MA with an onsite requirement of Monday-Wednesday every week.
Your impact:
The Senior Manager/Associate Director of Statistical Programming is responsible for providing clinical trial studies statistical programming leadership, strategic guidance and technical support of high-quality stats data outputs within Rapport’s Bipolar Mania program. This role is reporting directly to the head of statistical programming in the Biometrics group.
Your day-to-day:&nbsp;&nbsp;
<ul>
<li>Support Statistical Programming (SP) activities across all stages of clinical development (Phase I-IV), from protocol development design to clinical study report (CSR), health agency submission and post-marketing activities.</li>
<li>Review and understand study documents, including the Protocol, electronic case Report Forms (eCRFs), Statistical Analysis Plans (SAPs), Data Transfer Specification, CDISC Standard Data Tabulation Model (SDTM) and Analysis Dataset Model (ADaM) specification and CSR.</li>
<li>Serve as the clinical trial SP lead by developing, validating, and documenting SAS programs for SDTM, ADaM, and TFL outputs supporting CSRs, DSUR/IB updates, publications, and ad hoc, ISS and ISE deliverables.</li>
<li>Manage outsourcing strategy and oversee deliverables from CROs and external vendors.</li>
<li>Ensure compliance with industry standards (CDISC, ICH, FDA/EMA guidance) and company SOPs.</li>
<li>Provide programming oversight for regulatory submissions (e.g., NDA/BLA/MAA), including eCTD packages, define.xml, and reviewer guides (cSDRG and ADRG).</li>
<li>Engage the development and implementation of programming standards, automation tools, and quality control processes.</li>
<li>Collaborate with Biostatistics leadership to ensure integration of statistical and programming workflows.</li>
<li>Collaborate with statistical programmers at all levels to foster a strong, supportive, and motivated programming team.</li>
<li>Contribute to cross-functional initiatives to improve data quality, efficiency, and innovation in clinical development.</li>
</ul>
Must-Haves:
<ul>
<li>Master’s or Bachelor’s degree in Computer Science, Statistics, Mathematics, Life Sciences, or a related field.</li>
<li>8-10 years of experience in statistical programming within the biotech/pharmaceutical/CRO industry
<ul>
<li>Title and compensation commensurate with experience and education&nbsp;</li>
</ul>
</li>
<li>Expert-level proficiency in SAS (Base, Macro, STAT, GRAPH) and strong experience with CDISC standards (SDTM, ADaM) in clinical trials.</li>
<li>Strong SP clinical trial study project management skills and ability to manage multiple priorities in a fast-paced environment.</li>
<li>In-depth knowledge of clinical trial processes, GCP, regulatory requirements (FDA, EMA), and ICH guidelines.</li>
<li>Experience managing and developing high-performing teams, both internal and external (CRO/vendor).</li>
<li>Excellent interpersonal, communication, and leadership skills.</li>
<li>Experience supporting regulatory submissions, such as NDA, BLA, or MAA filings, is preferred.</li>
<li>Familiarity with R, Python, or other programming languages is a plus.</li>
<li>Experience in Neurology or CSN highly desirable.</li>
</ul>
What makes Rapport special:
<ul>
<li>Every role has meaning. We’re determined to discover a better way for patients, and you’ll feel the passion from the start.</li>
<li>We are driven to innovate. Exciting science that pushes boundaries and opens new possibilities.</li>
<li>Your perspective matters. Stick your neck out, share your ideas – we work as a team.</li>
<li>We have FUN. We hire smart, dedicated, down-to-earth people that you’ll enjoy spending time with.</li>
<li>Leadership that CARES – about you, your growth + development.</li>
<li>We're bicoastal. Whether you're in the lab full-time in San Diego or taking advantage of a more hybrid work schedule in Boston – we make the most of our time together.</li>
<li>Competitive benefits. Including unlimited PTO, a lifestyle spending account, commuting reimbursement, and much more!</li>
<li>You get to be YOU! Show up as you are and make every day count.</li>
</ul>
Your Compensation:
We get it. Compensation is an important part of your offer. You shouldn’t be surprised at the end of the recruiting process, and you should know that your offer is fair and equitable. How do we do this?&nbsp; We tell you about our hiring range now - we expect the hiring range for the role to be $200,000 to $220,000 for the Associate Director level. Our actual offer will reflect a lot of factors including your relevant skills, experience, location, salary market data, and internal equity. In addition to a competitive salary, we also offer a pretty great benefits package. We don’t stop here - if you join Rapport, we go to the next level. We share our full salary ranges for every level across our company.&nbsp;
Hybrid Work Environment:
We prioritize in person connection with our fellow Rapptors! Our team members come together onsite at our Boston office Monday-Wednesday to create more opportunities for innovation, collaboration, and connection.
&nbsp;<div class="content-conclusion">Rapport Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.
Note to Employment Agencies: Please do not forward any agency resumes. The company will not be responsible for any fees related to resumes that are unsolicited.
CCPA disclosure notice can be found <a href="https://www.rapportrx.com/privacy-policy/" target="_blank">here</a>.&nbsp;</div>

Senior Manager/Associate Director, Statistical Programming

<div class="content-intro">When our people share why they joined Rapport and love it here, it comes down to three things: the science, the mission, and the team. At Rapport, we’re driven by a passion for developing precision neuromedicines with the potential for fewer side effects, enabling patients and their families to enjoy healthier, more fulfilling lives. And we’re doing this with extraordinary science and awesome people (affectionately called Rapptors).&nbsp;
Our innovative scientific platform is centered on Receptor Associate Proteins (RAPs). RAPs are a component of neuronal receptor complexes, which play a crucial role in regulating receptor assembly and function. This precision approach has the potential to revolutionize the development of small molecule therapies. We are excited about the potential of our lead program, RAP-219. Our first indication targets focal epilepsy with additional clinical trials in primary generalized tonic-clonic seizures (PGTCS) and bipolar disorder.
The strength of Rapport comes from our Rapptors – who are united by our mission to improve patients lives. We bring the heart and hustle to advance our science forward, always staying true to our core values. We hope you’re as excited about this opportunity as we are!</div>We anticipate hiring for this role in mid-Q4.
&nbsp;
Your impact:
Rapport is seeking a Senior Manager / Associate Director of Biostatistics who will have a hands-on role in shaping the design, analysis, and interpretation of clinical trial data for our Bipolar Mania program. Reporting to the Head of Biostatistics, you will collaborate closely with multidisciplinary teams to advance groundbreaking therapies, ensuring statistical rigor and the highest standards of data integrity throughout the drug development process.
Your day-to-day:&nbsp;&nbsp;
<ul>
<li>Working as a leading statistician on multiple studies/projects. Oversee the production of protocol development (study design, endpoint selection, sample size calculation and statistical methods) and Statistical Analysis Plan (SAP) that lead to comprehensive clinical study reports suitable for regulatory submissions.</li>
<li>Provide strategic statistical leadership across development programs, influencing study design, data-driven decision-making, and regulatory strategies.</li>
<li>Support statistical programming to plan, execute and deliver SDTM and ADaM datasets, tables, listings, and figures (TLFs). Ensure compliance with CDISC standards (SDTM, ADaM) and regulatory guidelines (ICH, FDA, EMA).</li>
<li>Provide statistical input and the interpretation of results to clinical study reports, regulatory submissions documents, and publications, in collaboration with the clinical, regulatory, and medical affairs teams.</li>
<li>Perform and validate statistical analyses of clinical trial data using SAS and/or R in accordance with regulatory and internal standards.</li>
<li>Participate in the development and review of case report forms (CRFs) and data management plans to ensure accurate data collection aligned with study objectives.</li>
<li>Oversee and manage external CROs and vendors to ensure high-quality and timely deliverables.</li>
<li>Serve as the biometrics representative on cross-functional team, providing statistical support and insights to influence decision-making.</li>
</ul>
Must-Haves:
<ul>
<li>Senior Manager: PhD with 3+ or MS with 6+ years of biostatistics experience</li>
<li>Associate Director: PhD with 6+ years or MS with 9+ years of biostatistics experience</li>
<li>Experience in the CNS drug development and expertise in survival analysis and/or adaptive design is highly desirable</li>
<li>Skilled in scientific programming including SAS or R for data analysis, graphing, and simulation</li>
<li>Comprehensive knowledge of clinical trial design, advanced statistical analysis methods, and familiarity with regulatory guidelines (FDA, EMA, ICH)</li>
<li>Extensive knowledge of CDISC standards (SDTM, ADaM) and industry best practices for data collection, analysis, and reporting</li>
<li>Ability to communicate complex statistical concepts clearly to non-statistical audiences.</li>
<li>Ability to manage multiple projects in a fast-paced environment, flexibility to adapt to changing priorities and timelines</li>
<li>Ability to effectively collaborate with internal stakeholders and manage the statistical work of external stakeholders/vendors</li>
</ul>
What makes Rapport special:
<ul>
<li>Every role has meaning. We’re determined to discover a better way for patients, and you’ll feel the passion from the start.</li>
<li>We are driven to innovate. Exciting science that pushes boundaries and opens new possibilities.</li>
<li>Your perspective matters. Stick your neck out, share your ideas – we work as a team.</li>
<li>We have FUN. We hire smart, dedicated, down-to-earth people that you’ll enjoy spending time with.</li>
<li>Leadership that CARES – about you, your growth + development.</li>
<li>We're bicoastal. Whether you're in the lab full-time in San Diego or taking advantage of a more hybrid work schedule in Boston – we make the most of our time together.</li>
<li>Competitive benefits. Including unlimited PTO, a lifestyle spending account, commuting reimbursement, and much more!</li>
<li>You get to be YOU! Show up as you are and make every day count.</li>
</ul>
Your Compensation:
We get it. Compensation is an important part of your offer. You shouldn’t be surprised at the end of the recruiting process, and you should know that your offer is fair and equitable. How do we do this?&nbsp; We tell you about our hiring range now - we expect the hiring range for the role to be $200,000 to $220,000 for Associate Director level. Our actual offer will reflect a lot of factors including your relevant skills, experience, location, salary market data, and internal equity. In addition to a competitive salary, we also offer a pretty great benefits package. We don’t stop here - if you join Rapport, we go to the next level. We share our full salary ranges for every level across our company.&nbsp;
&nbsp;
&nbsp;<div class="content-conclusion">Rapport Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.
Note to Employment Agencies: Please do not forward any agency resumes. The company will not be responsible for any fees related to resumes that are unsolicited.
CCPA disclosure notice can be found <a href="https://www.rapportrx.com/privacy-policy/" target="_blank">here</a>.&nbsp;</div>

Senior Manager/Associate Director, Biostatistics

<div class="content-intro">When our people share why they joined Rapport and love it here, it comes down to three things: the science, the mission, and the team. At Rapport, we’re driven by a passion for developing precision neuromedicines with the potential for fewer side effects, enabling patients and their families to enjoy healthier, more fulfilling lives. And we’re doing this with extraordinary science and awesome people (affectionately called Rapptors).&nbsp;
Our innovative scientific platform is centered on Receptor Associate Proteins (RAPs). RAPs are a component of neuronal receptor complexes, which play a crucial role in regulating receptor assembly and function. This precision approach has the potential to revolutionize the development of small molecule therapies. We are excited about the potential of our lead program, RAP-219. Our first indication targets focal epilepsy with additional clinical trials in primary generalized tonic-clonic seizures (PGTCS) and bipolar disorder.
The strength of Rapport comes from our Rapptors – who are united by our mission to improve patients lives. We bring the heart and hustle to advance our science forward, always staying true to our core values. We hope you’re as excited about this opportunity as we are!</div>&nbsp;

We anticipate hiring for this role in mid-Q4.&nbsp;This role is located in Boston, MA with an onsite requirement of Monday-Wednesday every week.
&nbsp;
Your impact:
In this role, you’ll work with our Clinical Operations Lead to help keep our Bipolar Mania trials running smoothly. It’s a hands-on, high-impact role on a fun, driven team where you’ll grow fast and make a real difference.&nbsp;
Your day-to-day:&nbsp;&nbsp;
<ul>
<li>Provide support to the Clinical Operations Lead (COL) in the planning, execution, and oversight of a global phase 3 clinical trial from study start-up to close-out.</li>
<li>Support the development, review and tracking of study-related documents (protocols, ICFs, investigative brochure, monitoring visit reports, etc.) with cross functional team collaboration.</li>
<li>Support start-up activities to help accelerate country and site activations.</li>
<li>Oversee CRO and vendors, monitor performance metrics, and ensure timely and high-quality deliverables.</li>
<li>Track study timelines, enrollment, protocol deviations, data trends, and sample management in partnership with CRO and internal stakeholders.</li>
<li>Maintain and organize trial documentation (e.g., TMF/eTMF oversight, trackers, meeting minutes) ensuring that study documentation is in a continuous state of inspection readiness.&nbsp;&nbsp;&nbsp;</li>
<li>Contribute to inspection readiness activities and ensure compliance with GCP and SOPs.</li>
<li>Help identify and resolve site risks and/or issues to foster positive site relationships.</li>
<li>Coordinate internal team meetings and participate in cross-functional study meetings.</li>
<li>Proactively communicate study updates with key internal and external stakeholders.</li>
</ul>
Must-Haves:
<ul>
<li>Bachelor’s degree preferably in life sciences or healthcare related field.</li>
<li>6-8 years of clinical operations experience within the biotech or pharma industry required</li>
<li>Experience managing outsourced global clinical trials across Phase I–III.</li>
<li>Prior involvement in study start-up activities strongly preferred</li>
<li>Solid understanding of GCP, ICH guidelines, and the clinical development process.</li>
<li>Experience with clinical trial management systems (CTMS), eTMF, and other operational tools.</li>
<li>Ability to multitask and flex across projects as priorities and deadlines shift.</li>
<li>Highly organized with excellent communication and interpersonal skills.</li>
<li>Strong attention to detail and ability to multitask in a dynamic, fast-paced setting.</li>
<li>A collaborative team player that takes initiative.</li>
</ul>
What makes Rapport special:
<ul>
<li>Every role has meaning. We’re determined to discover a better way for patients, and you’ll feel the passion from the start.</li>
<li>We are driven to innovate. Exciting science that pushes boundaries and opens new possibilities.</li>
<li>Your perspective matters. Stick your neck out, share your ideas – we work as a team.</li>
<li>We have FUN. We hire smart, dedicated, down-to-earth people that you’ll enjoy spending time with.</li>
<li>Leadership that CARES – about you, your growth + development.</li>
<li>We're bicoastal. Whether you're in the lab full-time in San Diego or taking advantage of a more hybrid work schedule in Boston – we make the most of our time together.</li>
<li>Competitive benefits. Including unlimited PTO, a lifestyle spending account, commuting reimbursement, and much more!</li>
<li>You get to be YOU! Show up as you are and make every day count.</li>
</ul>
Your Compensation:
We get it. Compensation is an important part of your offer. You shouldn’t be surprised at the end of the recruiting process, and you should know that your offer is fair and equitable. How do we do this?&nbsp; We tell you about our hiring range now - we expect the hiring range for the role to be $165,000 to $185,000. Our actual offer will reflect a lot of factors including your relevant skills, experience, location, salary market data, and internal equity. In addition to a competitive salary, we also offer a pretty great benefits package. We don’t stop here - if you join Rapport, we go to the next level. We share our full salary ranges for every level across our company.&nbsp;
Hybrid Work Environment:
We prioritize in person connection with our fellow Rapptors! Our team members come together onsite at our Boston office Monday-Wednesday to create more opportunities for innovation, collaboration, and connection.
&nbsp;<div class="content-conclusion">Rapport Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.
Note to Employment Agencies: Please do not forward any agency resumes. The company will not be responsible for any fees related to resumes that are unsolicited.
CCPA disclosure notice can be found <a href="https://www.rapportrx.com/privacy-policy/" target="_blank">here</a>.&nbsp;</div>

Senior Clinical Trial Manager

<div class="content-intro">When our people share why they joined Rapport and love it here, it comes down to three things: the science, the mission, and the team. At Rapport, we’re driven by a passion for developing precision neuromedicines with the potential for fewer side effects, enabling patients and their families to enjoy healthier, more fulfilling lives. And we’re doing this with extraordinary science and awesome people (affectionately called Rapptors).&nbsp;
Our innovative scientific platform is centered on Receptor Associate Proteins (RAPs). RAPs are a component of neuronal receptor complexes, which play a crucial role in regulating receptor assembly and function. This precision approach has the potential to revolutionize the development of small molecule therapies. We are excited about the potential of our lead program, RAP-219. Our first indication targets focal epilepsy with additional clinical trials in primary generalized tonic-clonic seizures (PGTCS) and bipolar disorder.
The strength of Rapport comes from our Rapptors – who are united by our mission to improve patients lives. We bring the heart and hustle to advance our science forward, always staying true to our core values. We hope you’re as excited about this opportunity as we are!</div>
We anticipate hiring for this role in mid-Q4.&nbsp;The preferred location for this role is in Boston, MA with an onsite requirement of Monday-Wednesday every week.
Your impact:
The Associate Director, New Product Planning is a key member of cross-functional program teams, providing market insights, research, and analysis to inform the commercial strategy for pipeline assets from early discovery and clinical development through launch readiness. This individual will conduct market research and build rigorous forecasts, lead commercial opportunity assessments, and translate clinical, scientific, and market data into actionable strategic recommendations for senior leadership and cross-functional stakeholders. The ideal candidate combines strong analytical and financial modeling skills with strategic business judgment, and thrives in ambiguous, fast-moving environments typical of early-stage assets.
Your day-to-day:&nbsp;&nbsp;
Forecasting &amp; Analytics
<ul>
<li>Build, maintain, and continuously refine multi-year commercial forecasts (epidemiology-based and analog-based) for pipeline assets across multiple indications and geographies</li>
<li>Develop patient flow, market share, and pricing/access models to support investment decisions, licensing evaluations, and portfolio prioritization</li>
<li>Stress-test forecast assumptions through sensitivity analyses and scenario planning; clearly communicate key drivers, risks, and uncertainty ranges</li>
</ul>
&nbsp;
Commercial Opportunity Assessment
<ul>
<li>Lead end-to-end opportunity assessments for early- and mid-stage pipeline assets, including market sizing, competitive landscape analysis, unmet need evaluation, and target product profile (TPP) development through combination of primary and desktop research, and manage primary market research (physician, patient, payer) to inform positioning and forecast assumptions; manage relationships with external vendors/consultants</li>
<li>Partner with Discovery, Medical, Clinical Development, Regulatory, and Market Access to evaluate indication sequencing, target population definition, and differentiation strategy</li>
<li>Synthesize primary and secondary market research (KOL interviews, payer/provider surveys, syndicated data) into clear quantitative and qualitative outputs to guide investment and program-level decisions</li>
</ul>
&nbsp;
Strategic Planning &amp; Decision Support
<ul>
<li>Support in-licensing, out-licensing, and M&amp;A due diligence with commercial assessments and valuation inputs</li>
<li>Prepare materials for governance forums (portfolio reviews, program committees, board updates), presenting complex analyses in a clear, concise, and decision-ready format</li>
<li>Contribute to long-range portfolio planning, identifying lifecycle opportunities, and informing R&amp;D prioritization. Subject matter expert on market dynamics, TPP, and associated revenue opportunity for assigned programs.</li>
</ul>
&nbsp;
Cross-Functional Leadership
<ul>
<li>Partner closely with R&amp;D program teams to provide commercial input into program-level decision models (e.g., go/no-go criteria, indication sequencing, trial design trade-offs, target product profile refinement), ensuring commercial assumptions and market realities are reflected in development strategy</li>
<li>Represent the commercial perspective on program teams and governance forums, translating clinical development scenarios into commercial implications (revenue impact, competitive positioning, market access considerations) to inform R&amp;D investment decisions</li>
<li>Serve as a thought partner to Discovery, Development, Finance, and future Commercial teams throughout asset lifecycle planning</li>
<li>Experienced in managing relationships with external vendors and consultants supporting market research and forecasting workstreams</li>
</ul>
Travel:&nbsp;Ability to travel approximately 20% or more depending on business needs, and congress attendance
Must-Haves:
<ul>
<li>Bachelor's degree required; MBA, MPH, or advanced life sciences degree is a plus</li>
<li>5+ years of relevant experience in pharmaceutical/biotech commercial strategy, new product planning, or life sciences management consulting</li>
<li>Demonstrated expertise in building and defending complex forecasting models (Excel-based; familiarity with forecasting software a plus)</li>
<li>Strong track record of leading or contributing to commercial opportunity assessments, market sizing, and competitive intelligence analyses</li>
<li>Life science consulting experience (e.g., strategy consulting, commercial due diligence, or pharma-focused advisory) strongly preferred</li>
<li>Excellent analytical, quantitative, and financial modeling skills</li>
<li>Strong executive presence with the ability to communicate complex data clearly to senior leadership</li>
<li>Experience working cross-functionally across R&amp;D, Medical, Commercial, and Finance</li>
<li>Therapeutic area experience in neurology and/or psychiatry is a plus</li>
</ul>
What makes Rapport special:
<ul>
<li>Every role has meaning. We’re determined to discover a better way for patients, and you’ll feel the passion from the start.</li>
<li>We are driven to innovate. Exciting science that pushes boundaries and opens new possibilities.</li>
<li>Your perspective matters. Stick your neck out, share your ideas – we work as a team.</li>
<li>We have FUN. We hire smart, dedicated, down-to-earth people that you’ll enjoy spending time with.</li>
<li>Leadership that CARES – about you, your growth + development.</li>
<li>We're bicoastal. Whether you're in the lab full-time in San Diego or taking advantage of a more hybrid work schedule in Boston – we make the most of our time together.</li>
<li>Competitive benefits. Including unlimited PTO, a lifestyle spending account, commuting reimbursement, and much more!</li>
<li>You get to be YOU! Show up as you are and make every day count.</li>
</ul>
Your Compensation:
We get it. Compensation is an important part of your offer. You shouldn’t be surprised at the end of the recruiting process, and you should know that your offer is fair and equitable. How do we do this?&nbsp; We tell you about our hiring range now - we expect the hiring range for the role to be $205,000 to $225,000. Our actual offer will reflect a lot of factors including your relevant skills, experience, location, salary market data, and internal equity. In addition to a competitive salary, we also offer a pretty great benefits package. We don’t stop here - if you join Rapport, we go to the next level. We share our full salary ranges for every level across our company.&nbsp;
Hybrid Work Environment:
We prioritize in person connection with our fellow Rapptors! Our team members come together onsite at our Boston office Monday-Wednesday to create more opportunities for innovation, collaboration, and connection.
<div class="content-conclusion">Rapport Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.
Note to Employment Agencies: Please do not forward any agency resumes. The company will not be responsible for any fees related to resumes that are unsolicited.
CCPA disclosure notice can be found <a href="https://www.rapportrx.com/privacy-policy/" target="_blank">here</a>.&nbsp;</div>

Associate Director, New Product Planning

<div class="content-intro">When our people share why they joined Rapport and love it here, it comes down to three things: the science, the mission, and the team. At Rapport, we’re driven by a passion for developing precision neuromedicines with the potential for fewer side effects, enabling patients and their families to enjoy healthier, more fulfilling lives. And we’re doing this with extraordinary science and awesome people (affectionately called Rapptors).&nbsp;
Our innovative scientific platform is centered on Receptor Associate Proteins (RAPs). RAPs are a component of neuronal receptor complexes, which play a crucial role in regulating receptor assembly and function. This precision approach has the potential to revolutionize the development of small molecule therapies. We are excited about the potential of our lead program, RAP-219. Our first indication targets focal epilepsy with additional clinical trials in primary generalized tonic-clonic seizures (PGTCS) and bipolar disorder.
The strength of Rapport comes from our Rapptors – who are united by our mission to improve patients lives. We bring the heart and hustle to advance our science forward, always staying true to our core values. We hope you’re as excited about this opportunity as we are!</div>We anticipate hiring for this role in mid-Q4. This role is located in Boston, MA with an onsite requirement of Monday-Wednesday every week.
&nbsp;
Your impact:
Rapport Therapeutics is seeking an experienced, AI-forward Associate Director, Medical Writing to serve as a medical writing lead for clinical programs within the RAP-219 portfolio. This role will lead the planning, development, and delivery of high-quality clinical and regulatory documents aligned with program goals, regulatory requirements, and modern medical writing practices. The successful candidate will bring strong regulatory writing expertise, sound judgment in the use of AI-enabled tools and emerging technologies, and the ability to partner effectively across functions to resolve feedback, foster alignment, and keep complex documents and submissions moving forward.
This role reports directly to the Head of Medical Writing, ensuring alignment with departmental objectives and strategic direction.
Your day-to-day:&nbsp; 
<ul>
<li>Lead the development, writing, and review of key clinical and regulatory documents for the RAP-219 program, including clinical study protocols, clinical study reports, Investigator’s Brochures, briefing documents, and Module 2 summaries.</li>
<li>Collaborate with medical science, clinical operations, regulatory, biostatistics, pharmacovigilance, and other functions to ensure accurate, consistent, and strategically aligned document content; manage stakeholder input, reconcile differing perspectives, and drive timely resolution of conflicting feedback.</li>
<li>Provide strategic input and guidance on document content, structure, and timelines to support regulatory submissions and global health authority interactions.</li>
<li>Maintain up-to-date knowledge of regulatory medical writing standards, relevant regulatory guidelines, and advances in AI, automation, structured content, and digital technologies affecting regulatory documentation.</li>
<li>Evaluate and support implementation of AI-enabled tools and automation solutions to improve document development, quality control, content reuse, and workflow efficiency; assess benefits and limitations and help establish standards for compliant adoption.</li>
<li>Contribute to the development, modernization, and implementation of medical writing processes, templates, standards, and tools, with a focus on scalable approaches that improve quality, consistency, and operational efficiency.</li>
</ul>
Must-Haves:
<ul>
<li style="line-height: 1;">Minimum of 8+ years of relevant medical writing experience in the biopharmaceutical industry, with proven success leading the preparation of clinical and regulatory documentation.</li>
<li>Advanced degree in a scientific or health-related discipline preferred; equivalent combination of education and relevant regulatory medical writing experience may be considered.</li>
<li>Experience as a lead writer for late-phase clinical programs; CNS experience strongly preferred.</li>
<li>Thorough understanding of ICH, FDA, and EMA regulatory requirements for clinical and regulatory documents.</li>
<li>Demonstrated AI literacy and practical experience using, evaluating, or implementing AI-enabled tools, automation, structured content, content reuse, or other technologies to improve medical writing efficiency, consistency, and quality.</li>
<li>Strong judgment in the responsible use of AI, including the ability to validate AI-assisted outputs, identify risks and limitations, maintain data confidentiality, and ensure that final deliverables meet scientific, regulatory, and quality standards.</li>
<li>Excellent written and verbal communication skills, with strong attention to detail and the ability to manage multiple priorities.</li>
<li>Strong stakeholder management skills, including the ability to build trust with cross-functional partners, navigate ambiguity, manage competing priorities and perspectives, resolve disputes constructively, and foster alignment among diverse contributors.</li>
<li>Demonstrated leadership, project management, stakeholder management, and mentoring skills, with the ability to influence without authority and maintain momentum in complex, cross-functional document development processes.</li>
</ul>
What makes Rapport special:
<ul>
<li>Every role has meaning. We’re determined to discover a better way for patients, and you’ll feel the passion from the start.</li>
<li>We are driven to innovate. Exciting science that pushes boundaries and opens new possibilities.</li>
<li>Your perspective matters. Stick your neck out, share your ideas – we work as a team.</li>
<li>We have FUN. We hire smart, dedicated, down-to-earth people that you’ll enjoy spending time with.</li>
<li>Leadership that CARES – about you, your growth + development.</li>
<li>We're bicoastal. Whether you're in the lab full-time in San Diego or taking advantage of a more hybrid work schedule in Boston – we make the most of our time together.</li>
<li>Competitive benefits. Including unlimited PTO, a lifestyle spending account, commuting reimbursement, and much more!</li>
<li>You get to be YOU! Show up as you are and make every day count.</li>
</ul>
Your Compensation:
We get it. Compensation is an important part of your offer. You shouldn’t be surprised at the end of the recruiting process, and you should know that your offer is fair and equitable. How do we do this?&nbsp; We tell you about our hiring range now - we expect the hiring range for the role to be $185,000 to $205,000. Our actual offer will reflect a lot of factors including your relevant skills, experience, location, salary market data, and internal equity. In addition to a competitive salary, we also offer a pretty great benefits package. We don’t stop here - if you join Rapport, we go to the next level. We share our full salary ranges for every level across our company.&nbsp;
Hybrid Work Environment:
We prioritize in person connection with our fellow Rapptors! Our team members come together onsite at our Boston office Monday-Wednesday to create more opportunities for innovation, collaboration, and connection.
&nbsp;<div class="content-conclusion">Rapport Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.
Note to Employment Agencies: Please do not forward any agency resumes. The company will not be responsible for any fees related to resumes that are unsolicited.
CCPA disclosure notice can be found <a href="https://www.rapportrx.com/privacy-policy/" target="_blank">here</a>.&nbsp;</div>

Associate Director, Medical Writing

<div class="content-intro">When our people share why they joined Rapport and love it here, it comes down to three things: the science, the mission, and the team. At Rapport, we’re driven by a passion for developing precision neuromedicines with the potential for fewer side effects, enabling patients and their families to enjoy healthier, more fulfilling lives. And we’re doing this with extraordinary science and awesome people (affectionately called Rapptors).&nbsp;
Our innovative scientific platform is centered on Receptor Associate Proteins (RAPs). RAPs are a component of neuronal receptor complexes, which play a crucial role in regulating receptor assembly and function. This precision approach has the potential to revolutionize the development of small molecule therapies. We are excited about the potential of our lead program, RAP-219. Our first indication targets focal epilepsy with additional clinical trials in primary generalized tonic-clonic seizures (PGTCS) and bipolar disorder.
The strength of Rapport comes from our Rapptors – who are united by our mission to improve patients lives. We bring the heart and hustle to advance our science forward, always staying true to our core values. We hope you’re as excited about this opportunity as we are!</div>We anticipate hiring for this role in mid-Q4. The preferred location for this role is in Boston, MA with an onsite requirement of Monday-Wednesday every week.
&nbsp;
Your impact:
The Associate Director/Director of Regulatory Strategy will play a pivotal role in leading strategic regulatory initiatives for the bipolar indication of our lead program, RAP-219. 
Your day-to-day:&nbsp;&nbsp;
<ul>
<li>Create and implement innovative and effective regulatory strategies to support the development of Rapport late stage global drug development programs</li>
<li>Provide regulatory expertise and advice to cross-functional team members including clinical, clinical pharmacology, and nonclinical</li>
<li>Accountable for the maintenance of regulatory applications such as INDs, CTAs, NDAs, etc.</li>
<li>Identify regulatory risks, propose mitigation plans and communicate impact to senior leadership.</li>
<li>Serve as the regulatory lead on study teams, as assigned, and provide regulatory guidance regarding clinical development plans, trial design, endpoints, safety requirements, and submission strategy.</li>
<li>Ensure compliance with local and international submission requirements, manage regulatory CROs as applicable.</li>
<li>Represent Rapport as the point of contact for regulatory health authorities, as assigned, ensuring exemplary ethics and transparency within the company and with health authorities.</li>
<li>Lead preparation and execution of interactions with FDA, EMA, and other regulatory agencies include the coordinate meeting requests, briefing documents, and responses to regulatory questions.</li>
<li>Monitor and interpret evolving global regulatory landscape and advise project teams on potential impact to programs</li>
<li>Support portfolio planning and governance activities as needed.</li>
</ul>
Must-Haves:
<ul>
<li>Bachelor’s degree in a life science or related discipline</li>
<li>8-10 years of experience in the pharmaceutical or biotech industry, with significant Regulatory Affairs experience</li>
<li>Experience small molecule drug development preferred</li>
<li>Global drug development experience preferred</li>
<li>CNS experience, in particular psychiatric or neurology indications preferred</li>
<li>Ability to manage competing priorities, influence and integrate within a team, manage timelines and deliver on corporate and program goals.</li>
<li>Strong interpersonal skills and alignment with Rapport’s values and company culture</li>
<li>Must demonstrate strong leadership and team building skills, including experience with conflict resolution and real time problem solving.</li>
<li>Thorough understanding of the development phases within a fast-moving biopharmaceutical organization.</li>
<li>Exceptional written and verbal communication skills</li>
<li>&nbsp;</li>
</ul>
What makes Rapport special:
<ul>
<li>Every role has meaning. We’re determined to discover a better way for patients, and you’ll feel the passion from the start.</li>
<li>We are driven to innovate. Exciting science that pushes boundaries and opens new possibilities.</li>
<li>Your perspective matters. Stick your neck out, share your ideas – we work as a team.</li>
<li>We have FUN. We hire smart, dedicated, down-to-earth people that you’ll enjoy spending time with.</li>
<li>Leadership that CARES – about you, your growth + development.</li>
<li>We're bicoastal. Whether you're in the lab full-time in San Diego or taking advantage of a more hybrid work schedule in Boston – we make the most of our time together.</li>
<li>Competitive benefits. Including unlimited PTO, a lifestyle spending account, commuting reimbursement, and much more!</li>
<li>You get to be YOU! Show up as you are and make every day count.</li>
</ul>
Your Compensation:
We get it. Compensation is an important part of your offer. You shouldn’t be surprised at the end of the recruiting process, and you should know that your offer is fair and equitable. How do we do this?&nbsp; We tell you about our hiring range now - we expect the hiring range for the role to be $200,000 to $225,000. Our actual offer will reflect a lot of factors including your relevant skills, experience, location, salary market data, and internal equity. In addition to a competitive salary, we also offer a pretty great benefits package. We don’t stop here - if you join Rapport, we go to the next level. We share our full salary ranges for every level across our company.&nbsp;
Hybrid Work Environment:
We prioritize in person connection with our fellow Rapptors! Our team members come together onsite at our Boston office Monday-Wednesday to create more opportunities for innovation, collaboration, and connection.
&nbsp;<div class="content-conclusion">Rapport Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.
Note to Employment Agencies: Please do not forward any agency resumes. The company will not be responsible for any fees related to resumes that are unsolicited.
CCPA disclosure notice can be found <a href="https://www.rapportrx.com/privacy-policy/" target="_blank">here</a>.&nbsp;</div>

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